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Some coronary heart assault sufferers might not profit from beta blockers

New analysis challenges established medical observe that every one coronary heart assault sufferers ought to be on beta blockers. The examine -- by a analysis staff on the College of Leeds -- checked out sufferers who had a coronary heart assault however didn't endure coronary heart failure -- a complication of a coronary heart assault the place the center muscle is broken and ceases to operate correctly. It discovered that coronary heart assault sufferers who didn't have coronary heart failure didn't dwell any longer after being given beta blockers -- but round 95% of sufferers who fall into this class find yourself on the treatment. Beta blockers are a robust group of medicines which lower the exercise of the center and decrease blood strain. They're generally prescribed after a coronary heart assault, however they will have undesirable side-effects for some sufferers corresponding to dizziness and tiredness. Not all individuals who have their first cor...

Childhood weight problems causes lasting injury to the physique

Weight problems in childhood has long run well being implications stretching into maturity, a brand new examine within the journal  Weight problems Critiques  reveals. Inspecting knowledge collected from over 300,000 individuals throughout 18 research, researchers from the College of Surrey recognized elevated arterial injury and enhanced probability of pre diabetes in individuals who have been overweight in childhood. The injury , an elevated thickness of those very important arteries, heightens the probability of a person affected by a cardiovascular ailment, resembling coronary heart illness, in later life. Physique mass index (BMI), waist circumference and pores and skin fold thickness measurements of over 300,000 youngsters (common age of 10) have been assessed and in contrast with outcomes gathered from the identical individuals on common 25 years later. Researchers found that overweight youngsters have been pre disposed to 'pre-diabetes' (an lack of abilit...

Wearing a 'heart' on your sleeve can reduce stress

Researchers from the Department of Psychology at Royal Holloway, University of London assessed the calming effects of a new wearable device called doppel -- a wristband designed to actively reduce stress by using the intuitive responses that we all have to rhythm, and especially to heartbeats. Inate rhythm Humans naturally respond to rhythm. For example, the tempo of a song can naturally alter our breathing and heart rates. Slower tempos result in lower arousal and positive or calm emotional states, while we associate fast rhythms with arousing emotional states such as joy, excitement, surprise, fear or anger. Beyond music, several studies report similar effects in responses to biological rhythms, and the heartbeat is perhaps the most ubiquitous biological rhythm in nature. "High arousal is correlated with increased heart rate, whereas calmness is physiologically correlated with lower heart rate," said Professor Manos Tsakiris from the Department of Psychology. ...

Small molecule prevents blood clots without increasing bleeding risk

The new research out of University Hospitals (UH) Cleveland Medical Center, Case Western Reserve University School of Medicine, and the Cleveland Clinic reveals a previously unknown cell receptor interaction that, when manipulated with therapeutic molecules, safely prevents blood clots. Approximately 100,000 Americans die annually from blood clots, or thrombosis , according to the Centers for Disease Control and Prevention. "We have found a new thrombosis target that does not increase bleeding risk," said senior author Daniel I. Simon, MD, President, UH Cleveland Medical Center, Herman K. Hellerstein Chair of Cardiovascular Research, and Professor of Medicine at Case Western Reserve School of Medicine. "Our discovery indicates that you can identify a new pathway and target that mediates blood clotting, but does not affect our body's natural processes to stop bleeding, called hemostasis." The new pathway centers around a pair of protein receptors that help ...